Ligand Data
Ligand
| Name | CHEMBL1784070 |
| SMILES | C#CCNc1ncnc2sc3c(=O)n(-c4ccc(Br)cc4)cnc3c12 |
| InChIKey | KKUDURGNHUAQTM-UHFFFAOYSA-N |
| Type | small-molecule |
| External Links |
Structure
Properties
| Hydrogen bond acceptors | 7 |
| Hydrogen bond donors | 1 |
| Rotatable bonds | 3 |
| Molecular weight | 411.0 |
Bioactivity
| Receptor | Affinity (nM) | Potency (nM) | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Min | Avg | Max | Min | Avg | Max |
| mGlu1 | GRM1 | Human | Metabotropic glutamate | C (Glutamate) | 6.8 | 6.8 | 6.8 | |||