CHEMBL164471


SMILES O=C1c2ccoc2CCC1CCN1CCC(c2noc3cc(F)ccc23)CC1
InChIKey QKOGDLJCRXBSED-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 382.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Rat 5-Hydroxytryptamine A pKd 6.3 6.3 6.3 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.16 7.36 7.46 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 9.14 9.18 9.25 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.34 7.34 7.34 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database