CHEMBL108229


SMILES COc1ccccc1N1CCN(CCNC(=O)C2CCCCC2)CC1
InChIKey HJFABTUBWNFTBH-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 345.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Rat Dopamine A pKi 7.64 7.77 7.9 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 9.1 9.1 9.1 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pIC50 8.37 8.37 8.37 ChEMBL