CHEMBL1831166


SMILES COc1cc2c(cc1OC)CN(CCCCn1cc(-c3ccc(F)cc3)c3ccccc31)CC2
InChIKey SAUWBVJOXSKPQX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 8
Molecular weight (Da) 458.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pKi 6.26 6.26 6.26 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.9 5.9 5.9 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.82 5.82 5.82 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.06 6.06 6.06 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database