Chembl184242
Chemical Properties
| SMILES | Cc1cccnc1-c1cc(F)cc(-n2nnc(-c3ccccn3)n2)c1 |
| Hydrogen bond acceptors | 6 |
| Hydrogen bond donors | 0 |
| Rotatable bonds | 3 |
| Molecular weight | 332.1 |
Drug Properties
| Type | Small molecule |
| Endogenous | No |
| Approved | No |
| InChIKey | HKMADWWVHXTYHL-UHFFFAOYSA-N |
Bioactivity
| Receptor | Experimental Data | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| mGlu5 | GRM5 | Rat | Metabotropic glutamate | C | pIC50 | 7.51 | 7.51 | 7.51 | ChEMBL |
| mGlu5 | GRM5 | Rat | Metabotropic glutamate | C | pKi | 7.62 | 7.62 | 7.62 | ChEMBL |