Chembl184242

Chemical Properties

SMILES Cc1cccnc1-c1cc(F)cc(-n2nnc(-c3ccccn3)n2)c1
Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight 332.1

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey HKMADWWVHXTYHL-UHFFFAOYSA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Rat Metabotropic glutamate C pIC50 7.51 7.51 7.51 ChEMBL
mGlu5 GRM5 Rat Metabotropic glutamate C pKi 7.62 7.62 7.62 ChEMBL