CHEMBL184309
SMILES | CN(CCN1CCN(c2ccc(F)cc2F)CC1)c1nc(N)n2nc(-c3ccco3)nc2n1 |
InChIKey | DKCOTCJUXKLWCS-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 10 |
Hydrogen bond donors | 1 |
Rotatable bonds | 6 |
Molecular weight (Da) | 455.2 |
Drug properties
Molecular type | Small molecule |
Physiological/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
A2A | AA2AR | Rat | Adenosine | A | pKi | 8.4 | 8.4 | 8.4 | ChEMBL |
A1 | AA1R | Rat | Adenosine | A | pKi | 6.09 | 6.09 | 6.09 | ChEMBL |
A2A | AA2AR | Human | Adenosine | A | pKi | 8.4 | 8.4 | 8.4 | ChEMBL |
A1 | AA1R | Human | Adenosine | A | pKi | 6.09 | 6.09 | 6.09 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |