Chembl1911374
Chemical Properties
| SMILES | O=c1n(Cc2ccc(C(F)(F)F)nc2)nc2c(-c3ccncc3)c(-c3ccc(Cl)cc3)cnn12 |
| Hydrogen bond acceptors | 7 |
| Hydrogen bond donors | 0 |
| Rotatable bonds | 4 |
| Molecular weight | 482.1 |
Drug Properties
| Type | Small molecule |
| Endogenous | No |
| Approved | No |
| InChIKey | LOLQZUDLOOHVCH-UHFFFAOYSA-N |
Bioactivity
| Receptor | Experimental Data | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| CB1 | CNR1 | Rat | Cannabinoid | A | pIC50 | 7.43 | 7.43 | 7.43 | ChEMBL |
| CB1 | CNR1 | Rat | Cannabinoid | A | pKd | 7.54 | 7.72 | 7.91 | ChEMBL |
| CB1 | CNR1 | Human | Cannabinoid | A | pKd | 8.34 | 8.37 | 8.4 | ChEMBL |
| CB1 | CNR1 | Human | Cannabinoid | A | pKi | 7.92 | 7.92 | 7.92 | ChEMBL |