Chembl1911374

Chemical Properties

SMILES O=c1n(Cc2ccc(C(F)(F)F)nc2)nc2c(-c3ccncc3)c(-c3ccc(Cl)cc3)cnn12
Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight 482.1

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey LOLQZUDLOOHVCH-UHFFFAOYSA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CB1 CNR1 Rat Cannabinoid A pIC50 7.43 7.43 7.43 ChEMBL
CB1 CNR1 Rat Cannabinoid A pKd 7.54 7.72 7.91 ChEMBL
CB1 CNR1 Human Cannabinoid A pKd 8.34 8.37 8.4 ChEMBL
CB1 CNR1 Human Cannabinoid A pKi 7.92 7.92 7.92 ChEMBL