Ro 10-4548 [6797]



Ro 10-4548


SMILES COc1cc(N2CCN(CC(O)COc3ccccc3NC(C)=O)CC2)ccc1O
InChIKey MXZGRDMOUWOERR-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors 7
Hydrogen bond donors 3
Rotatable bonds 8
Log P 1.921
Molecular weight (Da) 415.2
Stereochemistry info unspecified

Database connections

Ligand site mutations D4

Bioactivities

Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database
Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database

Ro 10-4548


Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Distribution across phases (no. indications)

Phase I 0
Phase II 0
Phase III 0
Phase IV 0

Database connections

Ligand site mutations D4

Compound is not listed as a drug.