13,14-dihydro-16-m-chlorophenoxy-w-tetranor-PGF1α
| SMILES | O[C@@H](COc1cccc(c1)Cl)CC[C@H]1[C@H](O)C[C@@H]([C@@H]1CCCCCCC(=O)O)O |
| InChIKey | XECZBZWECQIBDA-LELZANKISA-N |
Chemical properties
| Hydrogen bond acceptors | 5 |
| Hydrogen bond donors | 4 |
| Rotatable bonds | 13 |
| Molecular weight (Da) | 428.2 |
Drug properties
| Molecular type | Small molecule |
| Physiological/Surrogate | Surrogate |
| Approved drug | No |
Database connections
Bioactivities
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| FP | PF2R | Human | Prostanoid | A | pIC50 | 8.6 | 8.8 | 9.0 | Guide to Pharmacology |
| EP1 | PE2R1 | Human | Prostanoid | A | pEC50 | 4.72 | 4.72 | 4.72 | ChEMBL |
| EP1 | PE2R1 | Human | Prostanoid | A | pIC50 | 5.87 | 5.87 | 5.87 | ChEMBL |
| EP2 | PE2R2 | Human | Prostanoid | A | pIC50 | 5.17 | 5.17 | 5.17 | ChEMBL |
| EP3 | PE2R3 | Human | Prostanoid | A | pIC50 | 5.51 | 5.51 | 5.51 | ChEMBL |
| FP | PF2R | Human | Prostanoid | A | pEC50 | 8.05 | 8.05 | 8.05 | ChEMBL |
| FP | PF2R | Human | Prostanoid | A | pIC50 | 8.59 | 8.79 | 9.0 | ChEMBL |
| TP | TA2R | Human | Prostanoid | A | pEC50 | 5.1 | 5.1 | 5.1 | ChEMBL |