CHEMBL1928126


SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2ccc(COCCOCCOCCOCCOCc3ccc(C(=O)NCCCCN4CCN(c5ccccc5OC)CC4)cc3)cc2)CC1
InChIKey BYUVKVSQQDHYKB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 13
Hydrogen bond donors 2
Rotatable bonds 32
Molecular weight (Da) 952.6

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1A Q9TSW7 Pig Adrenoceptors A pKi 8.96 8.96 8.96 ChEMBL
D1 DRD1 Pig Dopamine A pKi 6.27 6.27 6.27 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.17 7.17 7.17 ChEMBL
D3 DRD3 Human Dopamine A pKi 9.06 9.06 9.06 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.6 7.78 7.96 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database