Chembl1940408

Chemical Properties

SMILES Fc1ccc(CCCCN2CCN(c3ccc(Cl)cc3)CC2)cc1
Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight 346.2

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey ARWONURFSGKTJW-UHFFFAOYSA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 8.11 8.11 8.11 ChEMBL
D5 DRD5 Human Dopamine A pKi 5.75 5.75 5.75 ChEMBL
D1 DRD1 Human Dopamine A pKi 6.23 6.23 6.23 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.95 6.95 6.95 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.09 7.09 7.09 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.58 6.58 6.58 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.55 6.55 6.55 ChEMBL