CHEMBL1784540


SMILES Cc1nc(C#Cc2cc(C#N)cc([N+](=O)[O-])c2)cs1
InChIKey NYDDBVSTHZVPKD-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 1
Molecular weight (Da) 269.0

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Rat Metabotropic glutamate C pKi 9.44 9.44 9.44 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Rat Metabotropic glutamate C pIC50 8.58 8.58 8.58 ChEMBL