CHEMBL1946126


SMILES Fc1ccc(OCCCN2CCCN(c3ccc(Cl)cc3)CC2)cc1
InChIKey NLEQSFUEJXECJY-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 362.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 6.96 6.96 6.96 ChEMBL
H1 HRH1 Human Histamine A pKi 6.29 6.29 6.29 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.25 6.25 6.25 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.14 7.14 7.14 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.76 6.76 6.76 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.68 6.68 6.68 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database