CHEMBL1803023


SMILES COc1cc(CN2CCN(c3ccccc3OC)CC2)ccc1OCc1cn(CCCCCCCCn2cc(COc3ccc(CN4CCN(c5ccccc5OC)CC4)cc3OC)nn2)nn1
InChIKey ZMVCPWQWTYDCHV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 16
Hydrogen bond donors 0
Rotatable bonds 25
Molecular weight (Da) 928.5

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 8.27 8.27 8.27 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.51 7.51 7.51 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.6 7.7 7.8 ChEMBL
D1 DRD1 Pig Dopamine A pKi 6.68 6.68 6.68 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database