CHEMBL1803024


SMILES COc1cc(CN2CCN(c3ccccc3OC)CC2)ccc1OCCCc1cn(CCCCCCCCn2cc(CCCOc3ccc(CN4CCN(c5ccccc5OC)CC4)cc3OC)nn2)nn1
InChIKey JJIBAQPGIKFZRA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 16
Hydrogen bond donors 0
Rotatable bonds 29
Molecular weight (Da) 984.6

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Pig Dopamine A pKi 6.66 6.66 6.66 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.82 7.82 7.82 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.08 7.08 7.08 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.39 7.51 7.66 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database