ACTH
SMILES | None |
InChIKey | IDLFZVILOHSSID-OVLDLUHVSA-N |
Sequence | SYSMEHFRWGKPVGKKRRPVKVYPNGAEDESAEAFPLEF |
Chemical properties
Hydrogen bond acceptors | None |
Hydrogen bond donors | None |
Rotatable bonds | None |
Molecular weight (Da) |
Drug properties
Molecular type | Peptide |
Physiological/Surrogate | Endogenous |
Approved drug | Yes |
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
MC1 | MSHR | Human | Melanocortin | A | pKi | 8.6 | 8.6 | 8.6 | Guide to Pharmacology |
MC3 | MC3R | Human | Melanocortin | A | pKi | 7.06 | 7.06 | 7.06 | Guide to Pharmacology |
MC5 | MC5R | Human | Melanocortin | A | pKi | 5.0 | 5.0 | 5.0 | Guide to Pharmacology |
MC3 | MC3R | Human | Melanocortin | A | pKi | 8.15 | 8.15 | 8.15 | Drug Central |
MC2 | ACTHR | Mouse | Melanocortin | A | pKd | 8.01 | 8.01 | 8.01 | Drug Central |
MC1 | MSHR | Human | Melanocortin | A | pKi | 8.07 | 8.07 | 8.07 | Drug Central |
MC4 | MC4R | Human | Melanocortin | A | pKi | 8.21 | 8.21 | 8.21 | Drug Central |
MC4 | MC4R | Human | Melanocortin | A | pKi | 6.16 | 6.16 | 6.16 | Guide to Pharmacology |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |