CHEMBL195057


SMILES O=C(NC/C=C/CN1CCN(c2cccc(Cl)c2Cl)CC1)c1ccc(O)cc1
InChIKey HQPJIWFXJJJLTM-OWOJBTEDSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight (Da) 419.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pKi 8.76 9.19 9.4 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.18 7.63 7.86 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pIC50 9.0 9.0 9.0 ChEMBL
D2 DRD2 Human Dopamine A pIC50 8.08 8.08 8.08 ChEMBL