Mg2+
| SMILES | [Mg+2] |
| InChIKey | JLVVSXFLKOJNIY-UHFFFAOYSA-N |
Chemical properties
| Hydrogen bond acceptors | 0 |
| Hydrogen bond donors | 0 |
| Rotatable bonds | 0 |
| Molecular weight (Da) | 24.0 |
Drug properties
| Molecular type | Small molecule |
| Endogenous/Surrogate | Endogenous |
| Approved drug | No |
Database connections
Bioactivities
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| 5-HT1A | 5HT1A | Human | 5-Hydroxytryptamine | A | pKi | 7.7 | 7.85 | 8.0 | Guide to Pharmacology |
| 5-HT7 | 5HT7R | Mouse | 5-Hydroxytryptamine | A | pKi | 6.4 | 6.4 | 6.4 | Guide to Pharmacology |
| 5-HT7 | 5HT7R | Rat | 5-Hydroxytryptamine | A | pKi | 6.4 | 6.4 | 6.4 | Guide to Pharmacology |
| 5-HT2A | 5HT2A | Bovine | 5-Hydroxytryptamine | A | pKi | 6.75 | 6.75 | 6.75 | ChEMBL |
| D1 | DRD1 | Bovine | Dopamine | A | pKi | 5.21 | 5.21 | 5.21 | ChEMBL |
| D2 | DRD2 | Bovine | Dopamine | A | pKi | 7.36 | 7.36 | 7.36 | ChEMBL |
| 5-HT1B | 5HT1B | Rat | 5-Hydroxytryptamine | A | pKi | 7.77 | 7.77 | 7.77 | ChEMBL |
| α1D | ADA1D | Human | Adrenoceptors | A | pKi | 6.28 | 6.28 | 6.28 | ChEMBL |
| 5-HT7 | 5HT7R | Human | 5-Hydroxytryptamine | A | pKi | 6.08 | 6.08 | 6.08 | ChEMBL |
| 5-HT2B | 5HT2B | Human | 5-Hydroxytryptamine | A | pKi | 6.32 | 6.32 | 6.32 | ChEMBL |
| D2 | DRD2 | Rat | Dopamine | A | pKi | 6.07 | 6.64 | 7.38 | ChEMBL |
| 5-HT1A | 5HT1A | Rat | 5-Hydroxytryptamine | A | pKi | 7.34 | 7.88 | 8.42 | ChEMBL |
| 5-HT1A | 5HT1A | Human | 5-Hydroxytryptamine | A | pKi | 7.3 | 7.82 | 8.51 | ChEMBL |
| 5-HT1A | 5HT1A | Human | 5-Hydroxytryptamine | A | pKd | 8.0 | 8.0 | 8.0 | ChEMBL |
| 5-HT2A | 5HT2A | Human | 5-Hydroxytryptamine | A | pKi | 5.49 | 5.91 | 6.18 | ChEMBL |
| D3 | DRD3 | Human | Dopamine | A | pKi | 6.18 | 7.0 | 7.82 | ChEMBL |
| D2 | DRD2 | Human | Dopamine | A | pKi | 6.0 | 6.92 | 7.89 | ChEMBL |
| 5-HT1A | 5HT1A | Rat | 5-Hydroxytryptamine | A | pKi | 6.05 | 7.67 | 8.42 | PDSP Ki database |
| 5-HT1A | A0A4W2HQH6 | Hybrid cattle | 5-Hydroxytryptamine | A | pKi | 7.7 | 7.77 | 7.85 | PDSP Ki database |
| 5-HT1A | A0A4X1UTF5 | Pig | 5-Hydroxytryptamine | A | pKi | 7.58 | 7.58 | 7.58 | PDSP Ki database |
| 5-HT1A | 5HT1A | Chimpanzee | 5-Hydroxytryptamine | A | pKi | 7.01 | 7.58 | 8.4 | PDSP Ki database |
| 5-HT1D | 5HT1D | Human | 5-Hydroxytryptamine | A | pKi | 5.0 | 5.0 | 5.0 | PDSP Ki database |
| 5-HT1D | A0A4W2F4L6 | Hybrid cattle | 5-Hydroxytryptamine | A | pKi | 5.0 | 5.0 | 5.03 | PDSP Ki database |
| 5-HT2C | 5HT2C | Rat | 5-Hydroxytryptamine | A | pKi | 5.22 | 5.48 | 5.68 | PDSP Ki database |
| 5-HT2A | 5HT2A | Bovine | 5-Hydroxytryptamine | A | pKi | 5.87 | 5.87 | 5.87 | PDSP Ki database |
| 5-HT1A | 5HT1A | Human | 5-Hydroxytryptamine | A | pKi | 6.67 | 7.56 | 8.4 | PDSP Ki database |
| 5-HT2A | 5HT2A | Human | 5-Hydroxytryptamine | A | pKi | 6.86 | 6.86 | 6.86 | PDSP Ki database |
| 5-HT2B | 5HT2B | Human | 5-Hydroxytryptamine | A | pKi | 6.67 | 6.67 | 6.67 | PDSP Ki database |
| 5-HT2C | 5HT2C | Human | 5-Hydroxytryptamine | A | pKi | 6.31 | 6.31 | 6.31 | PDSP Ki database |
| 5-HT7 | 5HT7R | Rat | 5-Hydroxytryptamine | A | pKi | 6.42 | 6.42 | 6.43 | PDSP Ki database |
| 5-HT6 | 5HT6R | Mouse | 5-Hydroxytryptamine | A | pKi | 6.4 | 6.4 | 6.4 | PDSP Ki database |
| 5-HT4 | 5HT4R | Rat | 5-Hydroxytryptamine | A | pKi | 5.0 | 5.0 | 5.0 | PDSP Ki database |
| 5-HT1B | 5HT1B | Rat | 5-Hydroxytryptamine | A | pKi | 5.0 | 5.0 | 5.0 | PDSP Ki database |
| 5-HT1D | 5HT1D | Rat | 5-Hydroxytryptamine | A | pKi | 5.0 | 5.0 | 5.0 | PDSP Ki database |
| 5-HT2A | 5HT2A | Bornean orangutan | 5-Hydroxytryptamine | A | pKi | 6.07 | 6.07 | 6.07 | PDSP Ki database |
| 5-HT7 | 5HT7R | Human | 5-Hydroxytryptamine | A | pKi | 6.08 | 6.08 | 6.08 | PDSP Ki database |
| 5-HT2A | 5HT2A | Human | 5-Hydroxytryptamine | A | pKi | 8.18 | 8.18 | 8.18 | Drug Central |
| 5-HT2B | 5HT2B | Human | 5-Hydroxytryptamine | A | pKi | 8.19 | 8.19 | 8.19 | Drug Central |
| α1A | ADA1A | Human | Adrenoceptors | A | pKi | 8.19 | 8.19 | 8.19 | Drug Central |
| D2 | DRD2 | Human | Dopamine | A | pKi | 8.11 | 8.11 | 8.11 | Drug Central |
| D3 | DRD3 | Human | Dopamine | A | pKi | 8.21 | 8.21 | 8.21 | Drug Central |
| D4 | DRD4 | Human | Dopamine | A | pKi | 8.15 | 8.15 | 8.15 | Drug Central |
| 5-HT7 | 5HT7R | Mouse | 5-Hydroxytryptamine | A | pKi | 8.19 | 8.19 | 8.19 | Drug Central |
| 5-HT1A | 5HT1A | Rat | 5-Hydroxytryptamine | A | pKi | 8.07 | 8.07 | 8.07 | Drug Central |
| D1 | DRD1 | Bovine | Dopamine | A | pKi | 8.28 | 8.28 | 8.28 | Drug Central |
| 5-HT2A | 5HT2A | Bovine | 5-Hydroxytryptamine | A | pKi | 8.17 | 8.17 | 8.17 | Drug Central |
| D2 | DRD2 | Bovine | Dopamine | A | pKi | 8.13 | 8.13 | 8.13 | Drug Central |
| 5-HT1B | 5HT1B | Rat | 5-Hydroxytryptamine | A | pKi | 8.11 | 8.11 | 8.11 | Drug Central |
| 5-HT7 | 5HT7R | Rat | 5-Hydroxytryptamine | A | pKi | 8.19 | 8.19 | 8.19 | Drug Central |
| D2 | DRD2 | Rat | Dopamine | A | pKi | 8.16 | 8.16 | 8.16 | Drug Central |
| 5-HT2C | 5HT2C | Human | 5-Hydroxytryptamine | A | pKi | 5.64 | 5.64 | 5.64 | ChEMBL |
| 5-HT2C | 5HT2C | Human | 5-Hydroxytryptamine | A | pKi | 8.22 | 8.22 | 8.22 | Drug Central |
| α1D | ADA1D | Human | Adrenoceptors | A | pKi | 8.2 | 8.2 | 8.2 | Drug Central |
| α1A | ADA1A | Rat | Adrenoceptors | A | pKi | 5.85 | 5.85 | 5.85 | ChEMBL |
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| 5-HT2A | 5HT2A | Bovine | 5-Hydroxytryptamine | A | pIC50 | 5.0 | 5.0 | 5.0 | ChEMBL |
| α2A | ADA2A | Bovine | Adrenoceptors | A | pIC50 | 5.0 | 5.0 | 5.0 | ChEMBL |
| α1A | ADA1A | Bovine | Adrenoceptors | A | pIC50 | 4.8 | 4.8 | 4.8 | ChEMBL |
| D1 | DRD1 | Bovine | Dopamine | A | pIC50 | 4.57 | 4.57 | 4.57 | ChEMBL |
| D2 | DRD2 | Bovine | Dopamine | A | pIC50 | 5.4 | 5.4 | 5.4 | ChEMBL |
| 5-HT1B | 5HT1B | Rat | 5-Hydroxytryptamine | A | pIC50 | 4.58 | 4.74 | 4.9 | ChEMBL |
| M1 | ACM1 | Rat | Acetylcholine (muscarinic) | A | Potency | 4.65 | 4.7 | 4.75 | ChEMBL |
| α1D | ADA1D | Human | Adrenoceptors | A | pIC50 | 5.97 | 5.97 | 5.97 | ChEMBL |
| 5-HT2B | 5HT2B | Human | 5-Hydroxytryptamine | A | pIC50 | 6.12 | 6.12 | 6.12 | ChEMBL |
| D2 | DRD2 | Rat | Dopamine | A | pIC50 | 6.55 | 6.79 | 7.26 | ChEMBL |
| 5-HT1A | 5HT1A | Rat | 5-Hydroxytryptamine | A | pIC50 | 7.22 | 7.64 | 8.15 | ChEMBL |
| 5-HT1A | 5HT1A | Human | 5-Hydroxytryptamine | A | pEC50 | 6.73 | 7.25 | 7.82 | ChEMBL |
| 5-HT1A | 5HT1A | Human | 5-Hydroxytryptamine | A | pIC50 | 7.6 | 7.6 | 7.6 | ChEMBL |
| 5-HT2A | 5HT2A | Human | 5-Hydroxytryptamine | A | pIC50 | 5.64 | 5.64 | 5.64 | ChEMBL |
| D3 | DRD3 | Human | Dopamine | A | pIC50 | 7.36 | 7.36 | 7.36 | ChEMBL |
| D2 | DRD2 | Human | Dopamine | A | pIC50 | 6.49 | 6.49 | 6.49 | ChEMBL |
| 5-HT1A | 5HT1A | Human | 5-Hydroxytryptamine | A | pEC50 | 8.14 | 8.14 | 8.14 | Drug Central |
| 5-HT2C | 5HT2C | Rat | 5-Hydroxytryptamine | A | pIC50 | 8.22 | 8.22 | 8.22 | Drug Central |
| α1A | ADA1A | Bovine | Adrenoceptors | A | pIC50 | 8.32 | 8.32 | 8.32 | Drug Central |
| 5-HT2C | 5HT2C | Rat | 5-Hydroxytryptamine | A | pIC50 | 6.0 | 6.0 | 6.0 | ChEMBL |
| α1A | ADA1A | Rat | Adrenoceptors | A | pIC50 | 5.46 | 5.46 | 5.46 | ChEMBL |
| α2A | ADA2A | Bovine | Adrenoceptors | A | pIC50 | 8.3 | 8.3 | 8.3 | Drug Central |