ADX71743


SMILES CCc1nc2c(o1)CC(CC2=O)c1ccc(cc1C)C
InChIKey CPKZCQHJDFSOJT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 2
Molecular weight (Da) 269.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu7 GRM7 Human Metabotropic glutamate C pIC50 7.2 7.2 7.2 Guide to Pharmacology
mGlu7 GRM7 Rat Metabotropic glutamate C pIC50 7.1 7.1 7.1 Guide to Pharmacology
mGlu7 GRM7 Human Metabotropic glutamate C pIC50 7.2 7.2 7.2 ChEMBL
mGlu7 GRM7 Rat Metabotropic glutamate C pIC50 6.17 6.18 6.19 ChEMBL