Chembl1963417

Chemical Properties

SMILES COc1ccc(-n2nnnc2C(F)(F)F)cc1CN[C@H]1CCN(C(=O)CN(C)C(C)=O)C[C@H]1c1ccccc1
Hydrogen bond acceptors 8
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight 545.2

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey ARPMRCPKTHXPNZ-VXKWHMMOSA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NK1 NK1R Human Tachykinin A pIC50 10.08 10.08 10.08 ChEMBL