AIDA


SMILES OC(=O)c1ccc2c(c1)CCC2(N)C(=O)O
InChIKey LSTPKMWNRWCNLS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 3
Rotatable bonds 2
Molecular weight (Da) 221.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu1 GRM1 Rat Metabotropic glutamate C pKi 4.0 4.0 4.0 Guide to Pharmacology
mGlu2 GRM2 Rat Metabotropic glutamate C pKi 5.96 5.96 5.96 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu1 GRM1 Human Metabotropic glutamate C pA2 4.2 4.2 4.2 Guide to Pharmacology
mGlu1 GRM1 Human Metabotropic glutamate C pIC50 5.16 5.16 5.16 ChEMBL