CHEMBL1962770


SMILES COc1ccccc1N1CCN(C[C@H]2CCC(c3ccccc3)(c3ccccc3)[C@H]2O)CC1
InChIKey GZRLRTFOHXYECM-LXFBAYGMSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 442.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 6.78 6.78 6.78 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 7.41 7.41 7.41 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 7.17 7.17 7.17 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 9.25 9.25 9.25 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database