CHEMBL1813117


SMILES Cc1c(CC(=O)O)c2cc(Cl)ccc2n1C(=O)c1ccc(OC[C@@H]2CN(C)c3ccccc3O2)cc1
InChIKey FGWQXWPDBISCQU-NRFANRHFSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 504.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
FP PF2R Mouse Prostanoid A pKi 5.66 5.66 5.66 ChEMBL
DP1 PD2R Mouse Prostanoid A pKi 7.54 7.54 7.54 ChEMBL
EP2 PE2R2 Mouse Prostanoid A pKi 6.48 6.48 6.48 ChEMBL
IP PI2R Human Prostanoid A pKi 7.31 7.31 7.31 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
DP1 PD2R Mouse Prostanoid A pIC50 8.51 8.51 8.51 ChEMBL