CHEMBL1963008


SMILES O=S(=O)(NCCCCN1CCN(c2ccc(Cl)cc2)CC1)c1cnc2ccccc2c1
InChIKey QCCHEBRTWDZGAB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 458.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Rat Dopamine A pKi 6.79 6.79 6.79 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 6.11 6.11 6.11 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.47 6.47 6.47 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.51 6.51 6.51 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database