L-tryptophan


SMILES OC(=O)[C@H](Cc1c[nH]c2c1cccc2)N
InChIKey QIVBCDIJIAJPQS-VIFPVBQESA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 3
Rotatable bonds 3
Molecular weight (Da) 204.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Endogenous
Approved drug Yes

Database connections

Structure pdb 7M3E 7DD5 7DD7 7DTU 7DD6 7M3G 7DTV 7M3F

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2A ADA2A Human Adrenoceptors A pKi 8.2 8.5 8.8 Guide to Pharmacology
α2B ADA2B Human Adrenoceptors A pKi 6.2 6.2 6.2 Guide to Pharmacology
α2A ADA2A Human Adrenoceptors A pKi 8.25 8.25 8.25 PDSP Ki database
α2B ADA2B Human Adrenoceptors A pKi 6.19 6.19 6.19 PDSP Ki database
α2C ADA2C Human Adrenoceptors A pKi 6.8 6.8 6.8 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database