robalzotan


SMILES NC(=O)c1ccc(c2c1C[C@H](CO2)N(C1CCC1)C1CCC1)F
InChIKey MQTUXRKNJYPMCG-CYBMUJFWSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 318.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu2 GRM2 Human Metabotropic glutamate C pKi 5.0 5.0 5.0 Guide to Pharmacology
mGlu3 GRM3 Human Metabotropic glutamate C pKi 5.3 5.3 5.3 Guide to Pharmacology
mGlu3 GRM3 Human Metabotropic glutamate C pKi 6.39 6.39 6.39 ChEMBL
mGlu2 GRM2 Human Metabotropic glutamate C pKi 6.35 6.35 6.35 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu3 GRM3 Human Metabotropic glutamate C pEC50 5.52 5.52 5.52 ChEMBL
mGlu1 GRM1 Rat Metabotropic glutamate C pEC50 4.0 4.0 4.0 ChEMBL
mGlu2 GRM2 Rat Metabotropic glutamate C pEC50 6.32 6.51 6.7 ChEMBL
mGlu3 GRM3 Rat Metabotropic glutamate C pEC50 5.77 5.77 5.77 ChEMBL