anandamide
SMILES | CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)NCCO |
InChIKey | LGEQQWMQCRIYKG-DOFZRALJSA-N |
Chemical properties
Hydrogen bond acceptors | 2 |
Hydrogen bond donors | 2 |
Rotatable bonds | 16 |
Molecular weight (Da) | 347.3 |
Drug properties
Molecular type | Small molecule |
Physiological/Surrogate | Endogenous |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
CB1 | CNR1 | Human | Cannabinoid | A | pKi | 6.3 | 6.65 | 7.0 | Guide to Pharmacology |
CB2 | CNR2 | Human | Cannabinoid | A | pKi | 5.7 | 6.05 | 6.4 | Guide to Pharmacology |
CB1 | CNR1 | Rat | Cannabinoid | A | pKi | 5.24 | 6.79 | 7.66 | ChEMBL |
CB2 | CNR2 | Human | Cannabinoid | A | pKi | 6.43 | 6.68 | 6.8 | ChEMBL |
CB1 | CNR1 | Human | Cannabinoid | A | pKi | 5.75 | 7.02 | 7.96 | ChEMBL |
CB2 | CNR2 | Mouse | Cannabinoid | A | pKi | 5.71 | 5.71 | 5.71 | ChEMBL |
CB2 | CNR2 | Rat | Cannabinoid | A | pKi | 6.44 | 6.44 | 6.44 | ChEMBL |
CB1 | CNR1 | Mouse | Cannabinoid | A | pKi | 5.27 | 6.16 | 7.05 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
GPR18 | GPR18 | Human | GPR18, GPR55 and GPR119 | A | pEC50 | 5.42 | 5.42 | 5.42 | Guide to Pharmacology |
GPR55 | GPR55 | Human | GPR18, GPR55 and GPR119 | A | pEC50 | 7.74 | 7.74 | 7.74 | Guide to Pharmacology |
CB1 | CNR1 | Rat | Cannabinoid | A | pEC50 | 4.8 | 5.59 | 7.16 | ChEMBL |
CB1 | CNR1 | Rat | Cannabinoid | A | pIC50 | 7.4 | 7.4 | 7.4 | ChEMBL |
CB1 | CNR1 | Mouse | Cannabinoid | A | pEC50 | 6.44 | 6.44 | 6.44 | ChEMBL |
CB1 | CNR1 | Mouse | Cannabinoid | A | pIC50 | 4.92 | 6.17 | 7.41 | ChEMBL |