CHEMBL182866


SMILES Cc1cccc(C#Cc2cccc(-c3ccccc3)c2)n1
InChIKey VHWNDWXFKXVZJA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 1
Hydrogen bond donors 0
Rotatable bonds 1
Molecular weight (Da) 269.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Rat Metabotropic glutamate C pKi 6.0 6.0 6.0 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Rat Metabotropic glutamate C pIC50 6.2 6.2 6.2 ChEMBL