terazosin


SMILES COc1cc2nc([nH]c(=N)c2cc1OC)N1CCN(CC1)C(=O)C1CCCO1
InChIKey VCKUSRYTPJJLNI-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 387.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug Yes

Database connections

Ligand site mutations α1A α1B

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CB2 CNR2 Human Cannabinoid A pKi 5.31 5.31 5.31 ChEMBL
CB1 CNR1 Human Cannabinoid A pKi 6.13 6.13 6.13 ChEMBL
CB1 CNR1 Human Cannabinoid A pKi 6.14 6.14 6.14 PDSP Ki database
CB2 CNR2 Human Cannabinoid A pKi 5.31 5.31 5.31 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CB1 CNR1 Human Cannabinoid A pIC50 6.39 6.39 6.39 ChEMBL