CHEMBL187952


SMILES CN1CCC(C2CNc3ccc(NC(=O)c4ccc(F)cc4)cc32)CC1
InChIKey ZOXWMXLYVITJIL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 353.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1F 5HT1F Human 5-Hydroxytryptamine A pKi 8.02 8.05 8.07 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 5.64 5.64 5.64 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.6 6.61 6.62 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database