vilazodone


SMILES N#Cc1ccc2c(c1)c(CCCCN1CCN(CC1)c1ccc3c(c1)cc(o3)C(=O)N)c[nH]2
InChIKey SGEGOXDYSFKCPT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 7
Molecular weight (Da) 441.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug Yes

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Human Dopamine A pKi 7.54 7.54 7.54 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.26 7.26 7.26 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.29 6.29 6.29 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.65 6.65 6.65 ChEMBL
D5 DRD5 Human Dopamine A pKi 7.99 7.99 7.99 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database