Chembl2035983


SMILES C[C@@]1(c2cc(F)cc(F)c2)CNC2(CCCC2)C(=O)N1CC(=O)Nc1cnc2c(c1)C[C@@]1(C2)C(=O)Nc2ncccc21
InChIKey IDKKNSOZWQOAAS-KYJUHHDHSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 3
Rotatable bonds 4
Molecular weight (Da) 572.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections


Bioactivity

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
calcitonin-like CALRL Mouse Calcitonin B1 pKi 7.72 7.72 7.72 ChEMBL
calcitonin-like CALRL Rat Calcitonin B1 pKi 7.77 7.77 7.77 ChEMBL
calcitonin-like CALRL Human Calcitonin B1 pKd 9.84 9.84 9.84 ChEMBL
calcitonin-like CALRL Human Calcitonin B1 pIC50 9.47 9.55 9.64 ChEMBL
calcitonin-like CALRL Human Calcitonin B1 pKi 10.28 10.28 10.28 ChEMBL
CT CALCR Human Calcitonin B1 pKi 5.5 5.5 5.5 ChEMBL