CHEMBL2036782


SMILES CC(C)N1CCN[C@@H](C(=O)N2CCN(C(=O)Nc3ccc(Cl)c(Cl)c3)CC2)C1
InChIKey OOGWCCRYNCAIBK-QGZVFWFLSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 427.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CCR2 CCR2 Human Chemokine A pKd 8.46 8.46 8.46 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CCR2 CCR2 Rat Chemokine A pIC50 6.7 6.7 6.7 ChEMBL
CCR2 CCR2 Mouse Chemokine A pIC50 5.92 5.92 5.92 ChEMBL
CCR2 CCR2 Human Chemokine A pIC50 8.24 8.33 8.46 ChEMBL
CCR5 CCR5 Human Chemokine A pIC50 7.66 7.66 7.66 ChEMBL