Chembl2048766


SMILES c1cc2c(cc1CNc1ccc3c(c1)[C@@]14CCCC[C@H]1[C@@H](C3)N(CC1CC1)CC4)OCO2
InChIKey KSWCUTKFCRESFR-KSCKTEMCSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 430.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections


Bioactivity

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 7.7 7.7 7.7 ChEMBL
κ OPRK Human Opioid A pEC50 10.11 10.11 10.11 ChEMBL
κ OPRK Human Opioid A pKi 9.28 9.28 9.28 ChEMBL
μ OPRM Human Opioid A pIC50 9.68 9.68 9.68 ChEMBL
μ OPRM Human Opioid A pKi 9.77 9.77 9.77 ChEMBL