CHEMBL1923293


SMILES COc1cc(CN2CCN(c3ccc4c(c3)OCCO4)CC2)ccc1F
InChIKey OSBMHRHGAFUBCG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 358.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Human Dopamine A pKi 4.77 4.79 4.8 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.23 5.23 5.23 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.38 8.38 8.38 ChEMBL
D1 DRD1 Pig Dopamine A pKi 4.64 4.64 4.64 ChEMBL
5-HT2A 5HT2A Pig 5-Hydroxytryptamine A pKi 5.38 5.38 5.38 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database