carbacyclin


SMILES CCCCC[C@@H](/C=C/[C@H]1[C@H](O)C[C@H]2[C@@H]1C/C(=C\CCCC(=O)O)/C2)O
InChIKey XZFRIPGNUQRGPI-WLPVIMDJSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 3
Rotatable bonds 10
Molecular weight (Da) 350.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
DP1 PD2R Human Prostanoid A pKi 6.9 6.9 6.9 Guide to Pharmacology
EP1 PE2R1 Human Prostanoid A pKi 7.6 7.6 7.6 Guide to Pharmacology
EP3 PE2R3 Human Prostanoid A pKi 7.85 7.85 7.85 Guide to Pharmacology
EP4 PE2R4 Human Prostanoid A pKi 6.5 6.5 6.5 Guide to Pharmacology
FP PF2R Human Prostanoid A pKi 6.4 6.45 6.5 Guide to Pharmacology
IP PI2R Human Prostanoid A pKi 6.5 6.55 6.6 Guide to Pharmacology
TP TA2R Human Prostanoid A pKi 4.7 4.7 4.7 Guide to Pharmacology
EP3 PE2R3 Mouse Prostanoid A pKi 7.51 7.51 7.51 Guide to Pharmacology
EP4 PE2R4 Mouse Prostanoid A pKi 5.6 5.6 5.6 Guide to Pharmacology
IP PI2R Mouse Prostanoid A pKi 7.0 7.0 7.0 Guide to Pharmacology
EP2 PE2R2 Mouse Prostanoid A pKi 5.8 5.8 5.8 Guide to Pharmacology
EP2 PE2R2 Human Prostanoid A pKi 6.0 6.0 6.0 Guide to Pharmacology
FP PF2R Mouse Prostanoid A pKi 5.9 5.9 5.9 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database