CHEMBL208847


SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2cc3c4ccc(c3o2)CCc2ccc(cc2)CC4)CC1
InChIKey FNHANZYICZUWQM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 537.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Human Dopamine A pKi 6.11 6.11 6.11 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.85 6.85 6.85 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.72 6.72 6.72 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.8 7.8 7.8 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.77 6.92 7.08 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database