Chembl211017

Chemical Properties

SMILES Cc1ccc2cccc(OCc3c(Cl)ccc(S(=O)(=O)NC(C)(C)C(=O)N4CCN(CCN=C(N)N)CC4)c3Cl)c2n1
Hydrogen bond acceptors 7
Hydrogen bond donors 3
Rotatable bonds 10
Molecular weight 635.2

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey MJEAYKOHKNVCFD-UHFFFAOYSA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
B2 BKRB2 Human Bradykinin A pKi 8.0 8.0 8.0 ChEMBL
B2 BKRB2 Human Bradykinin A pKd 7.4 7.4 7.4 ChEMBL