CHEMBL2111527


SMILES COc1ccc(Br)cc1-c1nc(CNCCC2CCN(Cc3ccccc3)C2)co1
InChIKey PUTIADDALKYHRM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 9
Molecular weight (Da) 469.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 5.18 5.18 5.18 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.82 6.82 6.82 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.29 6.4 6.51 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.12 7.12 7.12 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database