CHEMBL196744


SMILES O=C(NCCCCN1CCN(c2cccc(Cl)c2Cl)CC1)c1ccc(F)cc1
InChIKey AGUZAIMBKPZTGP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 423.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Pig Dopamine A pKi 6.04 6.04 6.04 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.36 7.36 7.36 ChEMBL
D3 DRD3 Human Dopamine A pKi 9.28 9.28 9.28 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.22 7.22 7.22 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.75 7.76 7.77 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database