Chembl2113666


SMILES CN1CC[C@]23c4c5cccc4O[C@H]2C(=O)CC[C@@]3(NC(=O)/C=C/c2ccccc2Cl)[C@H]1C5
InChIKey IMIGYXVXIBPZFP-MOXYHQKCSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 448.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections


Bioactivity

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pEC50 10.0 10.0 10.0 ChEMBL
δ OPRD Human Opioid A pKi 10.1 10.1 10.1 ChEMBL
κ OPRK Human Opioid A pEC50 10.0 10.0 10.0 ChEMBL
κ OPRK Human Opioid A pKi 9.27 9.27 9.27 ChEMBL
μ OPRM Human Opioid A pEC50 10.4 10.4 10.4 ChEMBL
μ OPRM Human Opioid A pKi 9.82 9.82 9.82 ChEMBL