CHEMBL198580


SMILES O=C(N[C@H]1CCN(Cc2ccc(F)c(F)c2)C1)c1ccc(-c2cccs2)cc1
InChIKey VOFRSVXXPJCSAK-SFHVURJKSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 398.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 7.85 7.85 7.85 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.8 7.8 7.8 ChEMBL
D2 DRD2 Human Dopamine A pKi 4.75 4.75 4.75 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database