CHEMBL212631


SMILES COc1ccccc1N1CCN(Cc2cn3ccccc3n2)CC1
InChIKey QGLGNPCWSBQHAU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 322.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Pig 5-Hydroxytryptamine A pKi 5.23 5.23 5.23 ChEMBL
D1 DRD1 Pig Dopamine A pKi 4.7 4.7 4.7 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.55 8.55 8.55 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.66 5.66 5.66 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.41 5.41 5.41 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.0 6.35 6.96 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pEC50 8.35 8.43 8.52 ChEMBL