GPCRdb

carbamazepine

Agent/drug
Bioactivity

carbamazepine

SMILES	NC(=O)N1c2ccccc2C=Cc2ccccc21
InChIKey	FFGPTBGBLSHEPO-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	1
Hydrogen bond donors	1
Rotatable bonds	0
Molecular weight (Da)	236.1

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids DrugBank Drug Central GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT_1A	5HT1A	Human	5-Hydroxytryptamine	A	pKi	5.00	5.00	5.00	PDSP Ki database
5-HT_2C	5HT2C	Rat	5-Hydroxytryptamine	A	pKi	5.00	5.00	5.00	PDSP Ki database
D₁	DRD1	Human	Dopamine	A	pKi	5.00	5.00	5.00	PDSP Ki database
D₂	DRD2	Human	Dopamine	A	pKi	5.00	5.00	5.00	PDSP Ki database
FZD₈	FZD8	Human	Frizzled	F	pKd	4.77	4.77	4.77	Guide to Pharmacology
FZD₈	FZD8	Human	Frizzled	F	pKd	8.32	8.32	8.32	Drug Central
FZD₈	FZD8	Mouse	Frizzled	F	pKd	4.78	4.78	4.78	ChEMBL
H₁	HRH1	Human	Histamine	A	pKi	5.00	5.00	5.00	PDSP Ki database
H₁	HRH1	Human	Histamine	A	pKi	8.38	8.38	8.38	Drug Central

Showing 1 to 9 of 9 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

TSH	TSHR	Human	Glycoprotein hormone	A	Potency	5.20	5.20	5.20	ChEMBL

Showing 1 to 1 of 1 entry

carbamazepine

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	Yes

Clinical Trials

Phase I 0

Phase II 0

Phase III 0

Approved No

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids DrugBank Drug Central GPCRdb

Compound is not listed as a drug.