CHEMBL213336


SMILES Cc1cccc(C)c1C(=O)NN1c2ccc(Cl)cc2N=C(N2CCN(C)CC2)c2ccccc21
InChIKey IYRXIXGRSIJDNI-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 473.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D5 DRD5 Human Dopamine A pKi 7.51 7.51 7.51 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 6.1 6.1 6.1 ChEMBL
D1 DRD1 Human Dopamine A pKi 8.52 8.52 8.52 ChEMBL
D4 DRD4 Human Dopamine A pKi 5.73 5.73 5.73 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.66 8.66 8.66 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.54 6.54 6.54 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database