CHEMBL213424


SMILES Cc1cccc(N)c1C(=O)NN1c2ccc(Cl)cc2N=C(N2CCN(C)CC2)c2ccccc21
InChIKey SINCAXCRAGCJEY-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 2
Molecular weight (Da) 474.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D5 DRD5 Human Dopamine A pKi 7.24 7.24 7.24 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 6.34 6.34 6.34 ChEMBL
D1 DRD1 Human Dopamine A pKi 8.49 8.49 8.49 ChEMBL
D4 DRD4 Human Dopamine A pKi 5.32 5.32 5.32 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.54 8.54 8.54 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.99 5.99 5.99 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database