CR6086


SMILES O=C([C@H]1CC2(CCN1Cc1ccc(cc1)C(F)(F)F)CC2)NC1(CC1)c1ccc(cc1)C(=O)O
InChIKey CADWTPLFEZSAHM-OAQYLSRUSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight (Da) 472.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP4 PE2R4 Human Prostanoid A pKd 9.27 9.27 9.27 Guide to Pharmacology
EP4 PE2R4 Human Prostanoid A pKi 7.78 7.78 7.78 Guide to Pharmacology
EP4 PE2R4 Rat Prostanoid A pKd 8.71 8.71 8.71 Guide to Pharmacology
EP4 PE2R4 Mouse Prostanoid A pKd 8.67 8.67 8.67 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database