Chembl2152633


SMILES CCCN(CCN1CCN(c2ccc3[nH]ccc3c2)CC1)[C@H]1CCc2nc(N)sc2C1
InChIKey YQJXEYCSOAXZLM-FQEVSTJZSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 7
Molecular weight (Da) 438.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections


Bioactivity

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Rat Dopamine A pKi 8.66 8.66 8.66 ChEMBL
D2 DRD2 Rat Dopamine A pKi 7.41 7.41 7.41 ChEMBL
D3 DRD3 Human Dopamine A pEC50 8.9 8.9 8.9 ChEMBL
D2 DRD2 Human Dopamine A pEC50 8.53 8.53 8.53 ChEMBL