Chembl2152746


SMILES CCCN(CCN1CCN(C(=O)c2cc3ccccc3[nH]2)CC1)C1CCc2nc(N)sc2C1
InChIKey CPWJJWMVFFZCGJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 7
Molecular weight (Da) 466.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections


Bioactivity

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Rat Dopamine A pKi 8.34 8.54 8.73 ChEMBL
D2 DRD2 Rat Dopamine A pKi 5.97 6.02 6.07 ChEMBL
D3 DRD3 Human Dopamine A pEC50 9.59 9.59 9.59 ChEMBL
D2 DRD2 Human Dopamine A pEC50 6.94 6.94 6.94 ChEMBL