CHEMBL202616


SMILES C[C@@H](Cn1ccc2ccc3ncccc3c21)NCc1ccc2ccccc2c1
InChIKey HECOADMZVNOEPY-SFHVURJKSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 365.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.87 6.87 6.87 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.8 7.8 7.8 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.74 6.74 6.74 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pEC50 7.57 7.57 7.57 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pEC50 7.28 7.28 7.28 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pEC50 6.65 6.65 6.65 ChEMBL